Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells

Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells

Antigen-presenting cells (APCs) regulate the balance of our immune response toward microbes. Whereas immunogenic APCs boost inflammation and activate lymphocytes, the highly plastic cells can switch into a tolerogenic/suppressive phenotype that dampens and resolves the response. Thereby the initiall...

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Bibliographic Details
Main Authors: Dagmar Hildebrand, Mariel-Esther Eberle, Sabine Marie Wölfle, Franziska Egler, Delal Sahin, Aline Sähr, Konrad A. Bode, Klaus Heeg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
suppressive antigen-presenting cell
miRNA
hsa-miR-99b/let-7e/miR-125a cluster
signal transducer and activator of transcription 3
programmed death-ligand 1
indolamin-2,3-dioxygenase
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01224/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01224/full

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