Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation.
Alzheimer's disease (AD)-associated amyloid β peptide (Aβ) is one of the main actors in AD pathogenesis. Aβ is characterized by its high tendency to self-associate, leading to the generation of oligomers and amyloid fibrils. The elucidation of pathways and intermediates is crucial for the under...
Main Authors: | Martin Wolff, Dmitry Unuchek, Bo Zhang, Valentin Gordeliy, Dieter Willbold, Luitgard Nagel-Steger |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4449029?pdf=render |
Similar Items
-
Interference with Amyloid-β Nucleation by Transient Ligand Interaction
by: Tao Zhang, et al.
Published: (2019-06-01) -
Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering.
by: Bo Zhang-Haagen, et al.
Published: (2016-01-01) -
Immobilization of homogeneous monomeric, oligomeric and fibrillar Aβ species for reliable SPR measurements.
by: Daniel Frenzel, et al.
Published: (2014-01-01) -
Plasma amyloid-β oligomerization assay as a pre-screening test for amyloid status
by: Rosha Babapour Mofrad, et al.
Published: (2021-07-01) -
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
by: Lin Nan, et al.
Published: (2011-06-01)