METABOLISM LEAVES ITS MARK ON THE POWERHOUSE: RECENT PROGRESS IN POST-TRANSLATIONAL MODIFICATIONS OF LYSINE IN MITOCHONDRIA

METABOLISM LEAVES ITS MARK ON THE POWERHOUSE: RECENT PROGRESS IN POST-TRANSLATIONAL MODIFICATIONS OF LYSINE IN MITOCHONDRIA

Lysine modifications have been studied extensively in the nucleus, where they play pivotal roles in gene regulation and constitute one of the pillars of epigenetics. In the cytoplasm, they are critical to proteostasis. However, in the last decade we have also witnessed the emergence of mitochondria...

Full description

Bibliographic Details
Main Authors: Kyriakos N. Papanicolaou, Brian eO'Rourke, D. Brian eFoster
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Physiology
Subjects:
Acetylation
Heart
SIRTUIN
sirt3
succinylation
malonylation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00301/full

Similar Items

Similar Items