Severe Headache, Paraesthesias, Facial Diplegia and Pleocytosis: A Misleading Presentation of Guillain-Barré Syndrome

• Main Authors: Mohamed Reda Belkhribchia, Abderrahim Chekabab, Yahya Naji, Latifa Hadrane, Soufiane Hassar, Nissrine Louhab, Najib Kissani
• Format: Article
• Language: English
• Published: SMC MEDIA SRL 2021-01-01
• Series: European Journal of Case Reports in Internal Medicine
• Subjects: guillain-barré syndrome; bifacial weakness with paraesthesias; headache; pleocytosis; plasma exchange
• Online Access: https://www.ejcrim.com/index.php/EJCRIM/article/view/2211

Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy. Progressive limb weakness, diminished/absent reflexes, sensory disturbance, and variable autonomic dysfunction are its core clinical manifestations. Bifacial weakness with paraesthesias (BFP) is a rare regional variant of GBS and is characterized by simultaneous facial diplegia, distal paraesthesias and minimal or no motor weakness. The association of headache with classic GBS has been rarely reported in the literature, and has not yet been described in the BFP variant. Here we report a misleading case of BFP variant associated with severe headache and mild pleocytosis. The repetition of nerve conduction studies (NCS) was extremely beneficial in this confusing case.