High-Yield Soluble Expression and Simple Purification of the Antimicrobial Peptide OG2 Using the Intein System in Escherichia coli
OG2 is a modified antimicrobial peptide, that is, derived from the frog peptide Palustrin-OG1. It has high antimicrobial activity and low cytotoxicity, and it is therefore promising as a therapeutic agent. Both prokaryotic (Escherichia coli) and eukaryotic (Pichia pastoris) production host systems w...
Main Authors: | Yong-Gang Xie, Fei-Fei Han, Chao Luan, Hai-Wen Zhang, Jie Feng, Young-Jun Choi, Denis Groleau, Yi-Zhen Wang |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2013/754319 |
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