Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells

Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells

<p>Abstract</p> <p>Background</p> <p>Tissue factor (TF) is a transmembrane protein that acts as a receptor for activated coagulation factor VII (FVIIa), initiating the coagulation cascade. Recent studies demonstrate that expression of tumor-derived TF also mediates intr...

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Bibliographic Details
Main Authors: Alvarado Carlos S, Tang Hao, Zhu Ningxi, Gu Lubing, Fang Jun, Zhou Muxiang
Format: Article
Language:English
Published: BMC 2008-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/69

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