Nuclear DNA damages generated by reactive oxygen molecules (ROS) under oxidative stress and their relevance to human cancers, including ionizing radiation-induced neoplasia part II: Relation between ROS-induced DNA damages and human cancer
Oxidative stress (OS) occurs when the production of reactive oxygen species (ROS) overrides the body’s natural defence. When the cell nucleus represents the target, macromolecular damage may result in mutations. Cancer is a disease of mutations, and DNA damages that are not repaired or mis-repaired...
Main Authors: | Robert Nilsson, Ning-Ang Liu |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2020-12-01
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Series: | Radiation Medicine and Protection |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666555720300630 |
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