Decreased Copper in Alzheimer’s Disease Brain Is Predominantly in the Soluble Extractable Fraction

Alzheimer’s disease (AD) is the leading cause of dementia and represents a significant burden on the global economy and society. The role of transition metals, in particular copper (Cu), in AD has become of significant interest due to the dyshomeostasis of these essential elements, which can impart...

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Bibliographic Details
Main Authors: Alan Rembach, Dominic J. Hare, Monica Lind, Christopher J. Fowler, Robert A. Cherny, Catriona McLean, Ashley I. Bush, Colin L. Masters, Blaine R. Roberts
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.1155/2013/623241