Contrasting effects of nitric oxide and corticotropin- releasing factor within the dorsal periaqueductal gray on defensive behavior and nociception in mice

Contrasting effects of nitric oxide and corticotropin- releasing factor within the dorsal periaqueductal gray on defensive behavior and nociception in mice

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The anxiogenic and antinociceptive effects produced by glutamate N-methyl-D-aspartate receptor activation within the dorsal periaqueductal gray (dPAG) matter have been related to nitric oxide (NO) production, since injection of NO synthase (NOS) inhibitors reverses these effects. dPAG corticotropin-...

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Bibliographic Details
Main Authors: T.T. Miguel, K.S. Gomes, R.L. Nunes-de-Souza
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Nitric oxide
Corticotropin-releasing factor
Periaqueductal gray
Defensive behavior
Antinociception
Mice
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000400003&lng=en&tlng=en

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