Identification of mimotopes with diagnostic potential for Trypanosoma brucei gambiense variant surface glycoproteins using human antibody fractions.

Identification of mimotopes with diagnostic potential for Trypanosoma brucei gambiense variant surface glycoproteins using human antibody fractions.

BACKGROUND: At present, screening of the population at risk for gambiense human African trypanosomiasis (HAT) is based on detection of antibodies against native variant surface glycoproteins (VSGs) of Trypanosoma brucei (T.b.) gambiense. Drawbacks of these native VSGs include culture of infective T....

Full description

Bibliographic Details
Main Authors: Liesbeth Van Nieuwenhove, Philippe Büscher, Fatima Balharbi, Michael Humbert, Tessa Dieltjens, Yves Guisez, Veerle Lejon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3373652?pdf=render

Internet

http://europepmc.org/articles/PMC3373652?pdf=render

Similar Items