ROS Regulate Caspase-Dependent Cell Delamination without Apoptosis in the Drosophila Pupal Notum

ROS Regulate Caspase-Dependent Cell Delamination without Apoptosis in the Drosophila Pupal Notum

Summary: Thorax fusion occurs in the midline of the Drosophila pupal notum and involves epithelial cell delamination requiring apoptotic signaling. By genetic screening, we found that NADPH oxidases (Nox and Duox) associated with superoxide anion (O˙-2) are responsible for caspase-3 activation and d...

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Bibliographic Details
Main Authors: Yuya Fujisawa, Natsuki Shinoda, Takahiro Chihara, Masayuki Miura
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:iScience
Subjects:
Developmental Genetics
Molecular Genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306039

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http://www.sciencedirect.com/science/article/pii/S2589004220306039

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