Notching in the Posterior Border of the Ramus of Mandible in a Patient with Neurofibromatosis Type I – A Case Report

• Main Authors: Bhuvana Krishnamoorthy, Parul Singh, Suma Gundareddy N, Manisha Lakhanpal Sharma, Manu Dhillon
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2013-10-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: neurofibromatosis type i; mandible; neurofibromin
• Online Access: https://jcdr.net/articles/PDF/3534/90-%205952_E(C)_F(P)_PF1(HM).pdf

Neurofibromatosis Type I (NFI) is a relatively common hereditary, autosomal dominant neurocutaneous condition. It is a benign peripheral nerve sheath tumour arising from Schwann cells and peripheral fibroblasts. Even though it is a neurocutaneous disorder, NF I has significant skeletal manifestations. Oral and maxillofacial skeletal structures are also often involved in the form of deepening of sigmoid notch, enlarged mandibular canal and notching of inferior border of mandible. In this paper, we are reporting a female patient of NF I who presented with a notching in the posterior border of ascending ramus of mandible.