Hypothalamic–Pituitary and Adipose Tissue Responses to the Effect of Resistin in Sheep: The Integration of Leptin and Resistin Signaling Involving a Suppressor of Cytokine Signaling 3 and the Long Form of the Leptin Receptor

We hypothesized that resistin is engaged in the development of leptin central insensitivity/resistance in sheep, which is a unique animal model to explore reversible leptin resistance. Thirty Polish Longwool ewes, which were ovariectomized with estrogen replacement, were used. Treatments consisted o...

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Bibliographic Details
Main Authors: Dorota Anna Zieba, Weronika Biernat, Malgorzata Szczesna, Katarzyna Kirsz, Tomasz Misztal
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/9/2180