Sulfur Compounds as Inhibitors of Enzymatic Activity of a Snake Venom Phospholipase A<sub>2</sub>: Benzyl 4-nitrobenzenecarbodithioate as a Case of Study

Sulfur Compounds as Inhibitors of Enzymatic Activity of a Snake Venom Phospholipase A<sub>2</sub>: Benzyl 4-nitrobenzenecarbodithioate as a Case of Study

Snakebite is a neglected disease with a high impact in tropical and subtropical countries. Therapy based on antivenom has limited efficacy in local tissue damage caused by venoms. Phospholipases A<sub>2</sub> (PLA<sub>2</sub>) are enzymes that abundantly occur in snake venoms...

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Bibliographic Details
Main Authors: Isabel Henao Castañeda, Jaime Andrés Pereañez, Lina María Preciado, Jorge Jios
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
pla<sub>2</sub>
inhibitor
thioester
carbodithioate
molecular docking
snake venoms
Online Access:https://www.mdpi.com/1420-3049/25/6/1373

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