Sensitive method for determination of piplartine, an alkaloid amide from Piper species, in rat plasma samples by liquid chromatography-tandem mass spectrometry

Sensitive method for determination of piplartine, an alkaloid amide from Piper species, in rat plasma samples by liquid chromatography-tandem mass spectrometry

Piplartine (PPTN) is an alkaloid amide found in Piper species that presents different activities. PPTN determination in rat plasma is necessary to better understand its biological effects. The aim of this study was to develop a sensitive LC-MS/MS method for the determination of PPTN in rat plasma. T...

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Bibliographic Details
Main Authors:	Daniel P. Bezerra, Cláudia Pessoa, Manoel O. Moraes, Letícia V. Costa-Lotufo, Dayana Rubio Gouvea, Valquíria A. Polisel Jabor, Norberto Peporine Lopes, Keyller Bastos Borges, Mary Anne S. Lima, Edilberto R. Silveira
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Química 2012-01-01
Series:	Química Nova
Subjects:	piplartine LC-MS rat plasma analysis
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000300004&lng=en&tlng=en

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