Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report

Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report

Introduction: Despite adherence to current guidelines regarding dose adjustment and drug-level monitoring, beta-lactam-induced encephalopathy can still occur in the setting of chronic renal impairment. Case Report: We report what we believe is the first case of piperacillin- and tazobactam-induced...

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Main Authors: Chris Anthony, Meenal Sharma, Roberto Spina, Peter S Macdonald, Jacob Sevastos
Format: Article
Language:English
Published: SMC MEDIA SRL 2015-02-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Cefepime encephalopathy
Online Access:http://ejcrim.com/index.php/EJCRIM/article/view/172
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spelling doaj-9efaf394a5224b33b951ddaa787c3eef2020-11-25T01:01:49ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942015-02-012110.12890/2015_00017277Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case ReportChris Anthony0Meenal Sharma1Roberto Spina2Peter S Macdonald3Jacob Sevastos4Department of Cardiology, St Vincent’s Hospital, SydneyDepartment of Cardiology, St Vincent’s Hospital, SydneyDepartment of Cardiology, St Vincent’s Hospital, SydneyDepartment of Cardiology, St Vincent’s Hospital, SydneyDepartment of Nephrology, St Vincent’s Hospital, SydneyIntroduction: Despite adherence to current guidelines regarding dose adjustment and drug-level monitoring, beta-lactam-induced encephalopathy can still occur in the setting of chronic renal impairment. Case Report: We report what we believe is the first case of piperacillin- and tazobactam-induced encephalopathy in a patient with pre-existing cefepime-induced encephalopathy in the context of end-stage kidney disease despite adequate dose adjustment for renal impairment.http://ejcrim.com/index.php/EJCRIM/article/view/172Cefepime encephalopathy
collection DOAJ
language English
format Article
sources DOAJ
author Chris Anthony
Meenal Sharma
Roberto Spina
Peter S Macdonald
Jacob Sevastos
spellingShingle Chris Anthony
Meenal Sharma
Roberto Spina
Peter S Macdonald
Jacob Sevastos
Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report
European Journal of Case Reports in Internal Medicine
Cefepime encephalopathy
author_facet Chris Anthony
Meenal Sharma
Roberto Spina
Peter S Macdonald
Jacob Sevastos
author_sort Chris Anthony
title Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report
title_short Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report
title_full Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report
title_fullStr Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report
title_full_unstemmed Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report
title_sort dose-adjusted beta-lactam antibiotic-induced encephalopathy in a patient with end-stage renal impairment: a case report
publisher SMC MEDIA SRL
series European Journal of Case Reports in Internal Medicine
issn 2284-2594
publishDate 2015-02-01
description Introduction: Despite adherence to current guidelines regarding dose adjustment and drug-level monitoring, beta-lactam-induced encephalopathy can still occur in the setting of chronic renal impairment. Case Report: We report what we believe is the first case of piperacillin- and tazobactam-induced encephalopathy in a patient with pre-existing cefepime-induced encephalopathy in the context of end-stage kidney disease despite adequate dose adjustment for renal impairment.
topic Cefepime encephalopathy
url http://ejcrim.com/index.php/EJCRIM/article/view/172
work_keys_str_mv AT chrisanthony doseadjustedbetalactamantibioticinducedencephalopathyinapatientwithendstagerenalimpairmentacasereport
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AT robertospina doseadjustedbetalactamantibioticinducedencephalopathyinapatientwithendstagerenalimpairmentacasereport
AT petersmacdonald doseadjustedbetalactamantibioticinducedencephalopathyinapatientwithendstagerenalimpairmentacasereport
AT jacobsevastos doseadjustedbetalactamantibioticinducedencephalopathyinapatientwithendstagerenalimpairmentacasereport
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