Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report

Dose-Adjusted Beta-Lactam Antibiotic-Induced Encephalopathy in a Patient with End-Stage Renal Impairment: A Case Report

Introduction: Despite adherence to current guidelines regarding dose adjustment and drug-level monitoring, beta-lactam-induced encephalopathy can still occur in the setting of chronic renal impairment. Case Report: We report what we believe is the first case of piperacillin- and tazobactam-induced...

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Bibliographic Details
Main Authors: Chris Anthony, Meenal Sharma, Roberto Spina, Peter S Macdonald, Jacob Sevastos
Format: Article
Language:English
Published: SMC MEDIA SRL 2015-02-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Cefepime encephalopathy
Online Access:http://ejcrim.com/index.php/EJCRIM/article/view/172
Description
Summary:Introduction: Despite adherence to current guidelines regarding dose adjustment and drug-level monitoring, beta-lactam-induced encephalopathy can still occur in the setting of chronic renal impairment. Case Report: We report what we believe is the first case of piperacillin- and tazobactam-induced encephalopathy in a patient with pre-existing cefepime-induced encephalopathy in the context of end-stage kidney disease despite adequate dose adjustment for renal impairment.
ISSN:2284-2594

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