Large-Scale Analysis of Loss of Imprinting in Human Pluripotent Stem Cells

Large-Scale Analysis of Loss of Imprinting in Human Pluripotent Stem Cells

Summary: The parent-specific monoallelic expression of imprinted genes is controlled by DNA methylation marks that are established differentially in the germline. Perturbation of these marks leads to loss of imprinting (LOI), which is associated with developmental disorders and malignancy and may al...

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Bibliographic Details
Main Authors:	Shiran Bar, Maya Schachter, Talia Eldar-Geva, Nissim Benvenisty
Format:	Article
Language:	English
Published:	Elsevier 2017-05-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124717304953

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