Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus.

Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus.

The lithium-pilocarpine model of epilepsy reproduces in rodents several features of human temporal lobe epilepsy, by inducing an acute status epilepticus (SE) followed by a latency period. It has been proposed that the neuronal network reorganization that occurs during latency determines the subsequ...

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Bibliographic Details
Main Authors: Alicia Raquel Rossi, Maria Florencia Angelo, Alejandro Villarreal, Jerónimo Lukin, Alberto Javier Ramos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3826740?pdf=render

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