4-Hydroxy-2-Nonenal-Modified Glyceraldehyde-3-Phosphate Dehydrogenase Is Degraded by Cathepsin G in Rat Neutrophils

Degradation of oxidized or oxidatively modified proteins is an essential part of the antioxidant defenses of cells. 4-Hydroxy-2-nonenal, a major reactive aldehyde formed by lipid peroxidation, causes many types of cellular damage. It has been reported that 4-hydroxy-2-nonenal-modified proteins are d...

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Bibliographic Details
Main Authors: Yukihiro Tsuchiya, Go Okada, Shigeki Kobayashi, Toshiyuki Chikuma, Hiroshi Hojo
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2011/213686

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