Prefrontal Neuronal Excitability Maintains Cocaine-Associated Memory During Retrieval

Prefrontal Neuronal Excitability Maintains Cocaine-Associated Memory During Retrieval

Presentation of drug-associated cues provokes craving and drug seeking, and elimination of these associative memories would facilitate recovery from addiction. Emotionally salient memories are maintained during retrieval, as particular pharmacologic or optogenetic perturbations of memory circuits du...

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Bibliographic Details
Main Authors: James M. Otis, Michael K. Fitzgerald, Hanna Yousuf, Jake L. Burkard, Matthew Drake, Devin Mueller
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
intrinsic excitability
memory retrieval
cocaine abuse
PKA
norepinephrine
conditioned place preference (CPP)
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00119/full

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