Identification of Enolase as the Target of 2-Aminothiazoles in Mycobacterium tuberculosis
Tuberculosis is a massive global burden and Mycobacterium tuberculosis is increasingly resistant to first- and second-line drugs. There is an acute need for new anti-mycobacterial drugs with novel targets. We previously evaluated a series of 2-aminothiazoles with activity against Mycobacterium tuber...
Main Authors: | Heather H. Wescott, Edison S. Zuniga, Anumita Bajpai, Carolina Trujillo, Sabine Ehrt, Dirk Schnappinger, David M. Roberts, Tanya Parish |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-10-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2018.02542/full |
Similar Items
-
Editorial: New Approaches Against Drug-Resistant M. tuberculosis
by: Yossef Av-Gay, et al.
Published: (2021-04-01) -
Effects of diclazuril on the expression of enolase in second-generation merozoites of Eimeria tenella
by: Bian-hua Zhou, et al.
Published: (2020-12-01) -
Study to Find Out Predisposing Factors, Causality, Severity and Avoidability of Adverse Drug Reactions among Patients Treated under DOTS Centre of Northern India
by: Sachin Tutu, et al.
Published: (2019-06-01) -
Novel kinase platform for the validation of the anti-tubercular activities of Pelargonium sidoides (Geraniaceae)
by: V. Lukman, et al.
Published: (2020-09-01) -
Design, synthesis, and characterization of (1-(4-aryl)-1H-1,2,3-triazol-4-yl)methyl, substituted phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates against Mycobacterium tuberculosis
by: Venugopala KN, et al.
Published: (2016-08-01)