Lutein and Zeaxanthin Isomers Protect against Light-Induced Retinopathy via Decreasing Oxidative and Endoplasmic Reticulum Stress in BALB/cJ Mice

Lutein and Zeaxanthin Isomers Protect against Light-Induced Retinopathy via Decreasing Oxidative and Endoplasmic Reticulum Stress in BALB/cJ Mice

Oxidative stress (OS) and endoplasmic reticulum stress (ERS) are the major factors underlying photoreceptor degeneration. Lutein, RR-zeaxanthin (3R,3’R-zeaxanthin) and RS (meso)-zeaxanthin (3R,3’S-RS- zeaxanthin) (L/Zi) could protect against cell damage by ameliorating OS in reti...

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Bibliographic Details
Main Authors: Minzhong Yu, Weiming Yan, Craig Beight
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Nutrients
Subjects:
lutein
RR-zeaxanthin
mesozeaxanthin (RS zeaxanthin)
light damage
photoreceptor degeneration
oxidative stress
endoplasmic reticulum stress
electroretinography
Online Access:http://www.mdpi.com/2072-6643/10/7/842

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