Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity

G1-phase cyclin D1 (cD1) expression has been documented in post-mitotic neurons undergoing apoptosis, leading others to propose that attempted cell cycle re-entry may induce cell death. Here, cD1 immunoreactivity was found in a subpopulation of healthy excitatory neurons throughout the brain. Most s...

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Bibliographic Details
Main Authors: Hajira B. Koeller, M. Elizabeth Ross, Sara B. Glickstein
Format: Article
Language:English
Published: Elsevier 2008-08-01
Series:Neurobiology of Disease
Subjects:
CA1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000867