Oncogenic RAS drives the CRAF‐dependent extracellular vesicle uptake mechanism coupled with metastasis

Oncogenic RAS drives the CRAF‐dependent extracellular vesicle uptake mechanism coupled with metastasis

Abstract Oncogenic RAS impacts communication between cancer cells and their microenvironment, but it is unclear how this process influences cellular interactions with extracellular vesicles (EVs). This is important as intercellular EV trafficking plays a key role in cancer invasion and metastasis. H...

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Bibliographic Details
Main Authors: Dongsic Choi, Laura Montermini, Brian Meehan, Anthoula Lazaris, Peter Metrakos, Janusz Rak
Format: Article
Language:English
Published: Taylor & Francis Group 2021-06-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
macropinocytosis
metastasis
NHE
RAF
RAS
Online Access:https://doi.org/10.1002/jev2.12091

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