The Role of Notch, Hedgehog, and Wnt Signaling Pathways in the Resistance of Tumors to Anticancer Therapies

The Role of Notch, Hedgehog, and Wnt Signaling Pathways in the Resistance of Tumors to Anticancer Therapies

Resistance to therapy is the major hurdle in the current cancer management. Cancer cells often rewire their cellular process to alternate mechanisms to resist the deleterious effect mounted by different therapeutic approaches. The major signaling pathways involved in the developmental process, such...

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Bibliographic Details
Main Authors: Vivek Kumar, Mohit Vashishta, Lin Kong, Xiaodong Wu, Jiade J. Lu, Chandan Guha, B. S. Dwarakanath
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Notch signaling
Hedgehog signaling
Wnt signaling
tumors
resistance
anticancer
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.650772/full

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