Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa

Background: Long-term retention of adolescents aged 10 -19 years on antiretroviral therapy (ART) is crucial to achieve viral load suppression. However, it is reported globally that adolescents have lower retention in care (RiC) on ART, compared with children and adults. Objectives: To determine the...

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Main Authors: Brian van Wyk, Ebrahim Kriel, Ferdinand Mukumbang
Format: Article
Language:English
Published: AOSIS 2020-07-01
Series:Southern African Journal of HIV Medicine
Subjects:
hiv
Online Access:https://sajhivmed.org.za/index.php/hivmed/article/view/1077
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spelling doaj-9e86bec7191342b6aec313ac293265ce2020-11-25T03:34:41ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512020-07-01211e1e810.4102/sajhivmed.v21i1.1077692Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South AfricaBrian van Wyk0Ebrahim Kriel1Ferdinand Mukumbang2School of Public Health, Faculty of Community and Health Sciences, University of the Western Cape, Cape TownSchool of Public Health, Faculty of Community and Health Sciences, University of the Western Cape, Cape TownSchool of Public Health, Faculty of Community and Health Sciences, University of the Western Cape, Cape TownBackground: Long-term retention of adolescents aged 10 -19 years on antiretroviral therapy (ART) is crucial to achieve viral load suppression. However, it is reported globally that adolescents have lower retention in care (RiC) on ART, compared with children and adults. Objectives: To determine the prevalence and predictors of RiC of adolescents over 2 years following initiation onto ART in public health facilities in the Metropole District Health Services of the Western Cape province in 2013. Methods: Data of 220 adolescent patients who were newly initiated on ART in 2013 were extracted from the provincial electronic database, and subjected to univariate and bivariate analyses using SPSS. Results: The rate of RiC post-initiation was low throughout the study period, that is, 68.6%, 50.5% and 36.4% at 4, 12 and 24 months, respectively. The corresponding post-initiation viral load suppression levels on ART of those remaining in care and who had viral loads monitored were 84.1%, 77.4% and 68.8% at 4, 12 and 24 months, respectively. Retention in care after initiation on ART was higher amongst younger adolescents (10-14 years), compared with older adolescents (15-19 years). Male adolescents were significantly more likely to be retained, compared with females. Pregnant adolescents were significantly less likely to be retained compared with those who were not pregnant. Conclusion: Key interventions are needed to motivate adolescents to remain in care, and to adhere to their treatment regimen to achieve the target of 90% viral load suppression, with specific emphasis on older and pregnant adolescents.https://sajhivmed.org.za/index.php/hivmed/article/view/1077hivaidsadolescentsyouthretention in care
collection DOAJ
language English
format Article
sources DOAJ
author Brian van Wyk
Ebrahim Kriel
Ferdinand Mukumbang
spellingShingle Brian van Wyk
Ebrahim Kriel
Ferdinand Mukumbang
Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa
Southern African Journal of HIV Medicine
hiv
aids
adolescents
youth
retention in care
author_facet Brian van Wyk
Ebrahim Kriel
Ferdinand Mukumbang
author_sort Brian van Wyk
title Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa
title_short Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa
title_full Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa
title_fullStr Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa
title_full_unstemmed Retention in care for adolescents who were newly initiated on antiretroviral therapy in the Cape Metropole in South Africa
title_sort retention in care for adolescents who were newly initiated on antiretroviral therapy in the cape metropole in south africa
publisher AOSIS
series Southern African Journal of HIV Medicine
issn 1608-9693
2078-6751
publishDate 2020-07-01
description Background: Long-term retention of adolescents aged 10 -19 years on antiretroviral therapy (ART) is crucial to achieve viral load suppression. However, it is reported globally that adolescents have lower retention in care (RiC) on ART, compared with children and adults. Objectives: To determine the prevalence and predictors of RiC of adolescents over 2 years following initiation onto ART in public health facilities in the Metropole District Health Services of the Western Cape province in 2013. Methods: Data of 220 adolescent patients who were newly initiated on ART in 2013 were extracted from the provincial electronic database, and subjected to univariate and bivariate analyses using SPSS. Results: The rate of RiC post-initiation was low throughout the study period, that is, 68.6%, 50.5% and 36.4% at 4, 12 and 24 months, respectively. The corresponding post-initiation viral load suppression levels on ART of those remaining in care and who had viral loads monitored were 84.1%, 77.4% and 68.8% at 4, 12 and 24 months, respectively. Retention in care after initiation on ART was higher amongst younger adolescents (10-14 years), compared with older adolescents (15-19 years). Male adolescents were significantly more likely to be retained, compared with females. Pregnant adolescents were significantly less likely to be retained compared with those who were not pregnant. Conclusion: Key interventions are needed to motivate adolescents to remain in care, and to adhere to their treatment regimen to achieve the target of 90% viral load suppression, with specific emphasis on older and pregnant adolescents.
topic hiv
aids
adolescents
youth
retention in care
url https://sajhivmed.org.za/index.php/hivmed/article/view/1077
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