Survey of Differentially Methylated Promoters in Prostate Cancer Cell Lines

Survey of Differentially Methylated Promoters in Prostate Cancer Cell Lines

DNA methylation, copy number in the genomes of three immortalized prostate epithelial, five cancer cell lines (LNCaP, PC3, PC3M, PC3M-Pro4, PC3MLN4) were compared using a microarray-based technique. Genomic DNA is cut with a methylation-sensitive enzyme Hpall, followed by linker ligation, polymeras...

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Bibliographic Details
Main Authors: Yipeng Wang, Qiuju Yu, Ann H. Cho, Gaelle Rondeau, John Welsh, Eileen Adamson, Dan Mercola, Michael McClelland
Format: Article
Language:English
Published: Elsevier 2005-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
promoter
microarray
DNA methylation
CpG islands
gene silencing
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605801071

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