The Effects of Epigallocatechin Gallate (EGCG) on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)—A Next-Generation Sequencing and Bioinformatic Approach

The Effects of Epigallocatechin Gallate (EGCG) on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)—A Next-Generation Sequencing and Bioinformatic Approach

Idiopathic pulmonary fibrosis (IPF) is a disabling and lethal chronic progressive pulmonary disease. Epigallocatechin gallate (EGCG) is a polyphenol, which is the major biological component of green tea. The anti-oxidative, anti-inflammatory, and anti-fibrotic effects of EGCG have been shown in some...

Full description

Bibliographic Details
Main Authors:	Ming-Ju Tsai, Wei-An Chang, Ssu-Hui Liao, Kuo-Feng Chang, Chau-Chyun Sheu, Po-Lin Kuo
Format:	Article
Language:	English
Published:	MDPI AG 2019-04-01
Series:	International Journal of Molecular Sciences
Subjects:	bioinformatics fibroblast next-generation sequencing epigallocatechin gallate EGCG <i>PCSK9</i>
Online Access:	https://www.mdpi.com/1422-0067/20/8/1958

Similar Items

Antioxidant and antiviral activities of lipophilic epigallocatechin gallate (EGCG) derivatives
by: Ying Zhong, et al.
Published: (2012-01-01)

Synthesis and Biological Testing of Novel Glucosylated Epigallocatechin Gallate (EGCG) Derivatives
by: Xin Zhang, et al.
Published: (2016-05-01)

Effect of Guava Powder Addition on Epigallocatechin Gallate (EGCG) Content of Green Tea and Its Antioxidant Activity
by: Hanifah Ridha Rabbani, et al.
Published: (2020-03-01)

Intra-articular Injection of (-)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis
by: Hsuan-Ti Huang, et al.
Published: (2021-01-01)

Epigallocatechin gallate-β-lactoglobulin nanoparticles improve the antitumor activity of EGCG for inducing cancer cell apoptosis
by: Min Wu, et al.
Published: (2017-12-01)

Green Tea Catechin (-)-Epigallocatechin-3-Gallate (EGCG) Facilitates Fracture Healing
by: Sung-Yen Lin, et al.
Published: (2020-04-01)

Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression
by: Saleh A. Almatroodi, et al.
Published: (2020-06-01)

Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance
by: Rui-Qiang Zhao, et al.
Published: (2019-01-01)

Development and Optimization of Epigallocatechin-3-Gallate (EGCG) Nano Phytosome Using Design of Experiment (DoE) and Their In Vivo Anti-Inflammatory Studies
by: Mohammad H. Shariare, et al.
Published: (2020-11-01)

(−)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
by: Sung-Yen Lin, et al.
Published: (2018-12-01)

Efficacy of topical hydrogel Epigallocatechin-3-gallate against neutrophil cells in perforated dental pulp
by: Kun Ismiyatin, et al.
Published: (2020-06-01)

Bioavailability of Epigallocatechin Gallate Administered With Different Nutritional Strategies in Healthy Volunteers
by: Vicente Andreu Fernández, et al.
Published: (2020-05-01)

Molecular Targets of Epigallocatechin—Gallate (EGCG): A Special Focus on Signal Transduction and Cancer
by: Aide Negri, et al.
Published: (2018-12-01)

The Potential Roles of Epigallocatechin-3-Gallate in the Treatment of Ovarian Cancer: Current State of Knowledge
by: Bimonte S, et al.
Published: (2020-10-01)

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage
by: Kiran S. Avadhani, et al.
Published: (2017-01-01)

Uterine fibroid treatment with Vitamin D combined with Epigallocatechin gallate and Vitamin B6: a controlled pilot study
by: G. Porcaro, et al.
Published: (2021-03-01)

Antioxidant and Cytoprotective Effects of (−)-Epigallocatechin-3-(3″-<i>O</i>-methyl) Gallate
by: Eunji Kim, et al.
Published: (2019-08-01)

Preclinical Activities of Epigallocatechin Gallate in Signaling Pathways in Cancer
by: Mehdi Sharifi-Rad, et al.
Published: (2020-01-01)

Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?
by: Derliz Mereles, et al.
Published: (2011-08-01)

(-)-Epigallocatechin-3-Gallate Inhibits Arsenic-Induced Inflammation and Apoptosis through Suppression of Oxidative Stress in Mice
by: Nan-Hui Yu, et al.
Published: (2017-04-01)

Epigallocatechin Gallate (EGCG) Is the Most Effective Cancer Chemopreventive Polyphenol in Green Tea
by: Chong-Zhi Wang, et al.
Published: (2012-11-01)

Low Dose Epigallocatechin Gallate Alleviates Experimental Colitis by Subduing Inflammatory Cells and Cytokines, and Improving Intestinal Permeability
by: Yong Du, et al.
Published: (2019-07-01)

THE EFFECT OF GREEN TEA EXTRACT - EPIGALLOCATECHIN GALLATE (EGCG) ON PORCINE OVARIAN GRANULOSA CELL
by: Attila Kádasi, et al.
Published: (2014-02-01)

Epigallocatechin gallate in combination with Vitamin D3 and Vitamin B6 as a promising alternative in uterine fibroids management
by: L. Costabile, et al.
Published: (2021-04-01)

Amelioration of cisplatin sensitivity in human cervical cancer: Epigallocatechin-3-Gallate
by: Ulkan eKilic, et al.
Published: (2015-01-01)

Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts
by: Ran Wei, et al.
Published: (2019-10-01)

Assessment of Extraction Parameters on Antioxidant Capacity, Polyphenol Content, Epigallocatechin Gallate (EGCG), Epicatechin Gallate (ECG) and Iriflophenone 3-C-β-Glucoside of Agarwood (Aquilaria crassna) Young Leaves
by: Pei Yin Tay, et al.
Published: (2014-08-01)

Epigallocatechin Gallate: A Review of Its Beneficial Properties to Prevent Metabolic Syndrome
by: Samuel Legeay, et al.
Published: (2015-07-01)

Epigallocatechin Gallate for Management of Heavy Metal-Induced Oxidative Stress: Mechanisms of Action, Efficacy, and Concerns
by: Iwona Zwolak
Published: (2021-04-01)

Topical Application of Hyaluronic Acid-RGD Peptide-Coated Gelatin/Epigallocatechin-3 Gallate (EGCG) Nanoparticles Inhibits Corneal Neovascularization Via Inhibition of VEGF Production
by: Takuya Miyagawa, et al.
Published: (2020-04-01)

Epigallocatechin-3-O-(3-O-methyl)-gallate-induced Differentiation of Human Keratinocytes Involves Klotho-Mediated Regulation of Protein Kinase-cAMP Responsive Element-Binding Protein Signaling
by: Hyoung-June Kim, et al.
Published: (2014-04-01)

Involvement of MicroRNA-296 in the Inhibitory Effect of Epigallocatechin Gallate against the Migratory Properties of Anoikis-Resistant Nasopharyngeal Carcinoma Cells
by: Chien-Hung Lin, et al.
Published: (2020-04-01)

Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers
by: Yun-Ju Huang, et al.
Published: (2020-10-01)

(−)-Epigallocatechin-3-Gallate Inhibits the Life Cycle of Pseudorabies Virus In Vitro and Protects Mice Against Fatal Infection
by: Changchao Huan, et al.
Published: (2021-01-01)

Assessment Synergistic Effects of Integrated Therapy with Epigallocatechin-3-Gallate (EGCG) & Arsenic Trioxide and Irradiation on Breast Cancer Cell Line
by: Vahid CHANGIZI, et al.
Published: (2020-07-01)

The Effect of Ultrasound, Oxygen and Sunlight on the Stability of (−)-Epigallocatechin Gallate
by: Jiajun Zeng, et al.
Published: (2018-09-01)

Epigallocatechin gallate (EGCG) suppresses growth and tumorigenicity in breast cancer cells by downregulation of miR-25
by: Lingling Zan, et al.
Published: (2019-01-01)

Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model
by: Hsuan-Ti Huang, et al.
Published: (2021-12-01)

The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer’s disease: an overview of pre-clinical studies and translational perspectives in clinical practice
by: Marco Cascella, et al.
Published: (2017-06-01)

Monoalkylated Epigallocatechin-3-gallate (C18-EGCG) as Novel Lipophilic EGCG Derivative: Characterization and Antioxidant Evaluation
by: Cristina Minnelli, et al.
Published: (2020-03-01)