Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran

Introduction: Brucellosis is a zoonotic disease, which is associated with great economic and general health concerns. This is an endemic disease in Iran, and thus this study aimed to investigate its epidemiology and trend over a ten-year period in children hospitalized in northwest Iran Materials an...

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Main Authors: Iman Vafaii, Mohammad Ahangarzadeh Rezaee, Babak Abdinia, Kasra Kolahdouzan
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-10-01
Series:Patient Safety and Quality Improvement Journal
Subjects:
Online Access:http://psj.mums.ac.ir/article_11703_d41d8cd98f00b204e9800998ecf8427e.pdf
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spelling doaj-9e71d53dcba4421f96e1be5819bb526f2020-11-25T00:41:54ZengMashhad University of Medical SciencesPatient Safety and Quality Improvement Journal2345-44822345-44902018-10-01640010.22038/psj.2018.1170311703Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of IranIman Vafaii0Mohammad Ahangarzadeh Rezaee1Babak Abdinia2Kasra Kolahdouzan3Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.Introduction: Brucellosis is a zoonotic disease, which is associated with great economic and general health concerns. This is an endemic disease in Iran, and thus this study aimed to investigate its epidemiology and trend over a ten-year period in children hospitalized in northwest Iran Materials and Methods: A prospective study was conducted on children hospitalized with brucellosis diagnosis in the Tabriz Children's Hospital. Information of the patients, such as type of living place, age, history of consuming unpasteurized dairy products, family history of brucellosis in the past year, clinical symptoms, Wright's test, 2ME test, Coombs Wright test, onset date, diagnosis date, and treatment failure, was collected Results: Over a ten-year period, 59 medical records were extracted, out of which 21 subjects (35.6%) were female and 38 subjects (64.4%) were male. The mean age of involvement was 80.5 months. Among the patients, 66.1% and 33.9% were from rural and urban areas, respectively. In addition, 16.9% and 22% of patients had a history of contact with livestock, and 22% had a history of consuming unpasteurized dairy products. Moreover, 78.6% of patients had Wright’s test titers of ≥1:160 and 91.8% had Coombs test titers of ≥1:160. Blood culture results of 19 patients were available, out of which 21.1% were culture-positive Conclusion: Epidemiological studies assessing important risk factors for the spread of brucellosis in different regions across the world are very effective in disease control and prevention.This is the first report about epidemiology of children brucellosis in northwest Iranhttp://psj.mums.ac.ir/article_11703_d41d8cd98f00b204e9800998ecf8427e.pdfBrucellosisChildrenInfection
collection DOAJ
language English
format Article
sources DOAJ
author Iman Vafaii
Mohammad Ahangarzadeh Rezaee
Babak Abdinia
Kasra Kolahdouzan
spellingShingle Iman Vafaii
Mohammad Ahangarzadeh Rezaee
Babak Abdinia
Kasra Kolahdouzan
Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran
Patient Safety and Quality Improvement Journal
Brucellosis
Children
Infection
author_facet Iman Vafaii
Mohammad Ahangarzadeh Rezaee
Babak Abdinia
Kasra Kolahdouzan
author_sort Iman Vafaii
title Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran
title_short Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran
title_full Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran
title_fullStr Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran
title_full_unstemmed Epidemiology, Clinical Manifestations, Laboratory Findings and Outcome of Brucellosis in Hospitalized Children in Northwest of Iran
title_sort epidemiology, clinical manifestations, laboratory findings and outcome of brucellosis in hospitalized children in northwest of iran
publisher Mashhad University of Medical Sciences
series Patient Safety and Quality Improvement Journal
issn 2345-4482
2345-4490
publishDate 2018-10-01
description Introduction: Brucellosis is a zoonotic disease, which is associated with great economic and general health concerns. This is an endemic disease in Iran, and thus this study aimed to investigate its epidemiology and trend over a ten-year period in children hospitalized in northwest Iran Materials and Methods: A prospective study was conducted on children hospitalized with brucellosis diagnosis in the Tabriz Children's Hospital. Information of the patients, such as type of living place, age, history of consuming unpasteurized dairy products, family history of brucellosis in the past year, clinical symptoms, Wright's test, 2ME test, Coombs Wright test, onset date, diagnosis date, and treatment failure, was collected Results: Over a ten-year period, 59 medical records were extracted, out of which 21 subjects (35.6%) were female and 38 subjects (64.4%) were male. The mean age of involvement was 80.5 months. Among the patients, 66.1% and 33.9% were from rural and urban areas, respectively. In addition, 16.9% and 22% of patients had a history of contact with livestock, and 22% had a history of consuming unpasteurized dairy products. Moreover, 78.6% of patients had Wright’s test titers of ≥1:160 and 91.8% had Coombs test titers of ≥1:160. Blood culture results of 19 patients were available, out of which 21.1% were culture-positive Conclusion: Epidemiological studies assessing important risk factors for the spread of brucellosis in different regions across the world are very effective in disease control and prevention.This is the first report about epidemiology of children brucellosis in northwest Iran
topic Brucellosis
Children
Infection
url http://psj.mums.ac.ir/article_11703_d41d8cd98f00b204e9800998ecf8427e.pdf
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