Improving hexaminolevulinate enabled cancer cell detection in liquid biopsy immunosensors

Abstract Hexaminolevulinate (HAL) induced Protoporphyrin IX (PpIX) fluorescence is commonly used to differentiate cancer cells from normal cells in vivo, as for instance in blue light cystoscopy for bladder cancer diagnosis. A detailed approach is here provided to use this diagnostic principle ex vi...

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Bibliographic Details
Main Authors: Kit Man Chan, Jonathan Gleadle, Jordan Li, Thomas Danny Michl, Krasimir Vasilev, Melanie MacGregor
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86649-6