Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings

Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings

The molecular structure and properties of a three-layer system based on CaH2, P2O5, microcrystalline cellulose + miramistin deposited via a low-energy electron beam onto a wound dressing have been considered. A cross-linked cellulose layer containing carbon particles and a drug component serves as t...

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Main Authors: Yiming Liu, Xu Qin, A.V. Rogachev, A.A. Rogachev, I.I. Kontsevaya, A.E. Pyzh, Xiaohong Jiang, V.A. Yarmolenko, A.S. Rudenkov, M.A. Yarmolenko
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Electron-beam deposition
Microcrystalline cellulose
Miramistin
P2O5
Molecular structure
Drug release
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893921001146
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spelling doaj-9e6381575b1343bbb4aef21b851117c72021-09-09T04:29:54ZengElsevierCarbohydrate Polymer Technologies and Applications2666-89392021-12-012100146Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressingsYiming Liu0Xu Qin1A.V. Rogachev2A.A. Rogachev3I.I. Kontsevaya4A.E. Pyzh5Xiaohong Jiang6V.A. Yarmolenko7A.S. Rudenkov8M.A. Yarmolenko9International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, BelarusInternational Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, ChinaInternational Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, BelarusInternational Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus, 36, F. Skoriny, Minsk 220141, BelarusFrancisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, BelarusInstitute of Physiology National Academy of Sciences of Belarus, 28, Academicheskaya Street, Minsk 220072, BelarusInternational Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Corresponding authors.Gomel State Medical University, 5, Lange Street, Gomel 246000, BelarusInternational Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, BelarusInternational Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei Street, Nanjing 210094, China; Francisk Skorina Gomel State University, 104, Sovetskaya Street, Gomel 246019, Belarus; Corresponding authors.The molecular structure and properties of a three-layer system based on CaH2, P2O5, microcrystalline cellulose + miramistin deposited via a low-energy electron beam onto a wound dressing have been considered. A cross-linked cellulose layer containing carbon particles and a drug component serves as the coating. The cross-linked structure of the coating enhances the resistance of the miramistin to thermal degradation. The high sorption activity of the gauze substrate determines the exponential nature of the change in the miramistin concentration in the solution. The deposition of a three-layer coating (CaH2 + P2O5 + (cellulose + miramistin)) allows imparting prolonged antibacterial (E. coli, S. aureus) and antifungal (C. alibicans) properties to gauze dressings, reducing the rate of moisture desorption from its volume as a result of the hydrogel formation on the surface of the fibers. Here, the hydrogel formation affects the decrease (over two times) in the gauze's ability to sorb moisture.http://www.sciencedirect.com/science/article/pii/S2666893921001146Electron-beam depositionMicrocrystalline celluloseMiramistinP2O5Molecular structureDrug release
collection DOAJ
language English
format Article
sources DOAJ
author Yiming Liu
Xu Qin
A.V. Rogachev
A.A. Rogachev
I.I. Kontsevaya
A.E. Pyzh
Xiaohong Jiang
V.A. Yarmolenko
A.S. Rudenkov
M.A. Yarmolenko
spellingShingle Yiming Liu
Xu Qin
A.V. Rogachev
A.A. Rogachev
I.I. Kontsevaya
A.E. Pyzh
Xiaohong Jiang
V.A. Yarmolenko
A.S. Rudenkov
M.A. Yarmolenko
Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
Carbohydrate Polymer Technologies and Applications
Electron-beam deposition
Microcrystalline cellulose
Miramistin
P2O5
Molecular structure
Drug release
author_facet Yiming Liu
Xu Qin
A.V. Rogachev
A.A. Rogachev
I.I. Kontsevaya
A.E. Pyzh
Xiaohong Jiang
V.A. Yarmolenko
A.S. Rudenkov
M.A. Yarmolenko
author_sort Yiming Liu
title Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
title_short Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
title_full Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
title_fullStr Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
title_full_unstemmed Structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
title_sort structure and properties of microcellulose-based coatings deposited via a low-energy electron beam and their effect on the properties of onto wound dressings
publisher Elsevier
series Carbohydrate Polymer Technologies and Applications
issn 2666-8939
publishDate 2021-12-01
description The molecular structure and properties of a three-layer system based on CaH2, P2O5, microcrystalline cellulose + miramistin deposited via a low-energy electron beam onto a wound dressing have been considered. A cross-linked cellulose layer containing carbon particles and a drug component serves as the coating. The cross-linked structure of the coating enhances the resistance of the miramistin to thermal degradation. The high sorption activity of the gauze substrate determines the exponential nature of the change in the miramistin concentration in the solution. The deposition of a three-layer coating (CaH2 + P2O5 + (cellulose + miramistin)) allows imparting prolonged antibacterial (E. coli, S. aureus) and antifungal (C. alibicans) properties to gauze dressings, reducing the rate of moisture desorption from its volume as a result of the hydrogel formation on the surface of the fibers. Here, the hydrogel formation affects the decrease (over two times) in the gauze's ability to sorb moisture.
topic Electron-beam deposition
Microcrystalline cellulose
Miramistin
P2O5
Molecular structure
Drug release
url http://www.sciencedirect.com/science/article/pii/S2666893921001146
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