SERINC5 Potently Restricts Retrovirus Infection In Vivo

SERINC5 Potently Restricts Retrovirus Infection In Vivo

This study examined for the first time the in vivo function of the serine incorporator (SERINC) proteins during retrovirus infection. SERINC3 and SERINC5 (SERINC3/5) restrict a number of retroviruses, including human immunodeficiency virus 1 (HIV-1) and murine leukemia virus (MLV), by blocking their...

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Bibliographic Details
Main Authors: Uddhav Timilsina, Supawadee Umthong, Brian Lynch, Aimee Stablewski, Spyridon Stavrou
Format: Article
Language:English
Published: American Society for Microbiology 2020-07-01
Series:mBio
Subjects:
serinc3
serinc5
antiretroviral response
glycosylated gag
in vivo model
Online Access:https://doi.org/10.1128/mBio.00588-20

Internet

https://doi.org/10.1128/mBio.00588-20

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