MMP-2/9-Specific Activatable Lifetime Imaging Agent

MMP-2/9-Specific Activatable Lifetime Imaging Agent

Optical (molecular) imaging can benefit from a combination of the high signal-to-background ratio of activatable fluorescence imaging with the high specificity of luminescence lifetime imaging. To allow for this combination, both imaging techniques were integrated in a single imaging agent, a so-ca...

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Bibliographic Details
Main Authors: Marcus T.M. Rood, Marcel Raspe, Jan Bart ten Hove, Kees Jalink, Aldrik H. Velders, Fijs W.B. van Leeuwen
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Sensors
Subjects:
iridium
lifetime imaging
luminescence
enzymatic activation
MMP
FRET
fluorescence
Online Access:http://www.mdpi.com/1424-8220/15/5/11076

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