Interleukin-17 promotes the production of underglycosylated IgA1 in DAKIKI cells

Interleukin-17 promotes the production of underglycosylated IgA1 in DAKIKI cells

Background: Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. Methods: DAKIKI cells were cultured and stimul...

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Bibliographic Details
Main Authors: Jia-Ru Lin, Ji Wen, Hui Zhang, Li Wang, Fang-Fang Gou, Man Yang, Jun-Ming Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Renal Failure
Subjects:
Interleukin 17
IgA nephropathy
C1GALT1
Cosmc
underglycosylation
IgA1
Online Access:http://dx.doi.org/10.1080/0886022X.2017.1419972

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