Voluntary ethanol consumption induced by social isolation reverses the increase of α4/δ GABAA receptors gene expression and function in the hippocampus of C57BL/6J mice

Voluntary ethanol consumption induced by social isolation reverses the increase of α4/δ GABAA receptors gene expression and function in the hippocampus of C57BL/6J mice

Post-weaning social isolation (SI) is a model of prolonged mild stress characterized by behavioral and neurochemical alterations. We used SI in C57BL/6J mice to investigate the effects of ethanol (EtOH) in the free-choice drinking paradigm on gene expression and function of -aminobutyric acid type...

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Bibliographic Details
Main Authors: Enrico eSanna, Giuseppe eTalani, Nicola eObili, Maria Paola eMascia, Maria Cristina eMostallino, Pietro Paolo eSecci, Maria Giuseppina ePisu, Francesca eBiggio, Cinzia eUtzeri, Pierluigi eOlla, Giovanni eBiggio, Paolo eFollesa
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Neuroscience
Subjects:
Ethanol
Gene Expression
Hippocampus
Social Isolation
stress
patch clamp
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00015/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00015/full

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