Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice

SUMMARY A significant decline in human male reproductive function has been reported for the past 20 years but the molecular mechanisms remain poorly understood. However, recent studies showed that the gap junction protein connexin-43 (CX43; also known as GJA1) might be involved. CX43 is the predomin...

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Bibliographic Details
Main Authors: Sarah Giese, Hamid Hossain, Melanie Markmann, Trinad Chakraborty, Svetlin Tchatalbachev, Florian Guillou, Martin Bergmann, Klaus Failing, Karola Weider, Ralph Brehm
Format: Article
Language:English
Published: The Company of Biologists 2012-11-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/6/895

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