Preliminary Studies on Validation of Calu-3 Cell Line as a Model for Screening Respiratory Mucosa Irritation and Toxicity

Preliminary Studies on Validation of Calu-3 Cell Line as a Model for Screening Respiratory Mucosa Irritation and Toxicity

There is need to develop reproducible methods and experimental models for screening mucosal irritation and toxicity for drugs and pharmaceutical excipients. The aim of this study was to validate Calu-3 cell line as a model for screening respiratory irritation and toxicity of drugs and excipients. Ei...

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Bibliographic Details
Main Authors: Chibueze Ihekwereme, Charles Esimone, Di Shao, Remigius U. Agu
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Pharmaceutics
Subjects:
Calu-3 cells
MTT
toxicity prediction
mucosal toxicity
Online Access:http://www.mdpi.com/1999-4923/6/2/268

Internet

http://www.mdpi.com/1999-4923/6/2/268

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