Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma

Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma

Inducible genetically defined mouse models of cancer uniquely facilitate the investigation of early events in cancer progression, however, there are valid concerns about the ability of such models to faithfully recapitulate human disease. We developed an inducible mouse model of progressive lung ade...

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Bibliographic Details
Main Authors: Sarah Neidler, Björn Kruspig, Kay Hewit, Tiziana Monteverde, Katarina Gyuraszova, Attila Braun, William Clark, Daniel James, Ann Hedley, Bernhard Nieswandt, Emma Shanks, Craig Dick, Daniel J. Murphy
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
lung adenocarcinoma
KRAS
MYC
ERBB
Mouse models of cancer
RNA-SEQ
Online Access:https://www.mdpi.com/2072-6694/11/5/600

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