Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination

Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination

<p>Abstract</p> <p>Recent publications put a serious warning regarding the inefficacy of sulphadoxine-pyrimethamine (SP) for the intermittent preventive treatment of malaria in young children (IPTi). Recommendations for other therapies are being made. By using a different and bette...

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Main Author: Jansen Frans
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/70
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spelling doaj-9e0e234ce9054a3da2d25982d3786d862020-11-25T01:32:31ZengBMCMalaria Journal1475-28752011-03-011017010.1186/1475-2875-10-70Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combinationJansen Frans<p>Abstract</p> <p>Recent publications put a serious warning regarding the inefficacy of sulphadoxine-pyrimethamine (SP) for the intermittent preventive treatment of malaria in young children (IPTi). Recommendations for other therapies are being made. By using a different and better sulphonamide (sulphamethoxypyrazine), it is possible to manufacture fixed dose combination pills with artesunate and pyrimethamine. This combination permits a full therapy over 24 hours (dosing interval being 12 hours). It is recommended that this combination should be tested in future field studies of IPTi.</p> http://www.malariajournal.com/content/10/1/70
collection DOAJ
language English
format Article
sources DOAJ
author Jansen Frans
spellingShingle Jansen Frans
Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
Malaria Journal
author_facet Jansen Frans
author_sort Jansen Frans
title Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
title_short Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
title_full Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
title_fullStr Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
title_full_unstemmed Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
title_sort intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination
publisher BMC
series Malaria Journal
issn 1475-2875
publishDate 2011-03-01
description <p>Abstract</p> <p>Recent publications put a serious warning regarding the inefficacy of sulphadoxine-pyrimethamine (SP) for the intermittent preventive treatment of malaria in young children (IPTi). Recommendations for other therapies are being made. By using a different and better sulphonamide (sulphamethoxypyrazine), it is possible to manufacture fixed dose combination pills with artesunate and pyrimethamine. This combination permits a full therapy over 24 hours (dosing interval being 12 hours). It is recommended that this combination should be tested in future field studies of IPTi.</p>
url http://www.malariajournal.com/content/10/1/70
work_keys_str_mv AT jansenfrans intermittentpreventivetherapyformalariaargumentsinfavourofartesunateandsulphamethoxypyrazinepyrimethaminecombination
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