Effects of Mitophagy on Regulatory T Cell Function in Patients With Myasthenia Gravis

Effects of Mitophagy on Regulatory T Cell Function in Patients With Myasthenia Gravis

Objective: This study was conducted to determine whether regulatory T cells (CD4+CD25+T, Tregs) show abnormal mitophagy as well as the function of Tregs in patients with myasthenia gravis (MG).Methods: CD4+T cells and CD4+CD25+Treg cells were obtained from 15 patients with MG (MG group) and 15 contr...

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Bibliographic Details
Main Authors: Na Wang, Jiang Yuan, Md Rezaul Karim, Ping Zhong, Yan-Peng Sun, Hong-Yan Zhang, Yun-Fu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neurology
Subjects:
myasthenia gravis
mitophagy
regulatory T cell
rapamycin
3-methyladenine
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00238/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00238/full

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