Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases

Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-sp...

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Main Authors:	N.Vijayakameswara Rao, Jun Gi Rho, Wooram Um, Pramod Kumar EK, Van Quy Nguyen, Byeong Hoon Oh, Wook Kim, Jae Hyung Park
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Pharmaceutics
Subjects:	hyaluronic acid drug conjugates polymeric nanoparticles tumor-targeting targeted-therapy inflammatory diseases
Online Access:	https://www.mdpi.com/1999-4923/12/10/931

id	doaj-9e03fc19f78941fa8242985ca8e80e0d
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spelling	doaj-9e03fc19f78941fa8242985ca8e80e0d2020-11-25T01:46:22ZengMDPI AGPharmaceutics1999-49232020-09-011293193110.3390/pharmaceutics12100931Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory DiseasesN.Vijayakameswara Rao0Jun Gi Rho1Wooram Um2Pramod Kumar EK3Van Quy Nguyen4Byeong Hoon Oh5Wook Kim6Jae Hyung Park7School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaDepartment of Molecular Science & Technology, Ajou University, Suwon 16499, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaDepartment of Molecular Science & Technology, Ajou University, Suwon 16499, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaOwing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases.https://www.mdpi.com/1999-4923/12/10/931hyaluronic aciddrug conjugatespolymeric nanoparticlestumor-targetingtargeted-therapyinflammatory diseases
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	N.Vijayakameswara Rao Jun Gi Rho Wooram Um Pramod Kumar EK Van Quy Nguyen Byeong Hoon Oh Wook Kim Jae Hyung Park
spellingShingle	N.Vijayakameswara Rao Jun Gi Rho Wooram Um Pramod Kumar EK Van Quy Nguyen Byeong Hoon Oh Wook Kim Jae Hyung Park Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases Pharmaceutics hyaluronic acid drug conjugates polymeric nanoparticles tumor-targeting targeted-therapy inflammatory diseases
author_facet	N.Vijayakameswara Rao Jun Gi Rho Wooram Um Pramod Kumar EK Van Quy Nguyen Byeong Hoon Oh Wook Kim Jae Hyung Park
author_sort	N.Vijayakameswara Rao
title	Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases
title_short	Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases
title_full	Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases
title_fullStr	Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases
title_full_unstemmed	Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases
title_sort	hyaluronic acid nanoparticles as nanomedicine for treatment of inflammatory diseases
publisher	MDPI AG
series	Pharmaceutics
issn	1999-4923
publishDate	2020-09-01
description	Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases.
topic	hyaluronic acid drug conjugates polymeric nanoparticles tumor-targeting targeted-therapy inflammatory diseases
url	https://www.mdpi.com/1999-4923/12/10/931
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Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases

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