Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes

TF IIB-related factor 1 (Brf1) is a key transcription factor of RNA polymerase III (Pol III) genes. Our early studies have demonstrated that Brf1 and Pol III genes are epigenetically modulated by histone H3 phosphorylation. Here, we have further investigated the relationship of the abnormal expressi...

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Bibliographic Details
Main Authors: Teng Wu, Dongkun Zhang, Mingen Lin, Lihong Yu, Ting Dai, Shuai Li, Fenghai Yu, Lei Lu, Liling Zheng, Shuping Zhong
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/5554932