Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells

Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells

Purpose. TRPV1 is a multimodal channel mainly expressed in sensory neurons. We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific anta...

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Bibliographic Details
Main Authors:	Daniel Alvarez-Berdugo, Marcel Jiménez, Pere Clavé, Laia Rofes
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/184526

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