Expression and regulation of HIF-1alpha in macrophages under inflammatory conditions; significant reduction of VEGF by CaMKII inhibitor

Expression and regulation of HIF-1alpha in macrophages under inflammatory conditions; significant reduction of VEGF by CaMKII inhibitor

<p>Abstract</p> <p>Background</p> <p>Macrophages expressing the pro-angiogenic transcription factor hypoxia-inducible factor (HIF)-1alpha have been demonstrated in rheumatoid arthritis (RA) in the synovial tissue. Aim of the present study was to investigate intracellula...

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Bibliographic Details
Main Authors: van Leeuwen Miek A, Doornbos-van der Meer Berber, van Roosmalen Ingrid AM, Brouwer Elisabeth, Westra Johanna, Posthumus Marcel D, Kallenberg Cees GM
Format: Article
Language:English
Published: BMC 2010-03-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/11/61

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http://www.biomedcentral.com/1471-2474/11/61

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