Erythrocytic mobilization enhanced by the granulocyte colony-stimulating factor is associated with reduced anthrax-lethal-toxin-induced mortality in mice.

Erythrocytic mobilization enhanced by the granulocyte colony-stimulating factor is associated with reduced anthrax-lethal-toxin-induced mortality in mice.

Anthrax lethal toxin (LT), one of the primary virulence factors of Bacillus anthracis, causes anthrax-like symptoms and death in animals. Experiments have indicated that levels of erythrocytopenia and hypoxic stress are associated with disease severity after administering LT. In this study, the gran...

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Main Authors: Hsin-Hou Chang, Ya-Wen Chiang, Ting-Kai Lin, Guan-Ling Lin, You-Yen Lin, Jyh-Hwa Kau, Hsin-Hsien Huang, Hui-Ling Hsu, Jen-Hung Wang, Der-Shan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4226491?pdf=render

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