Comparing enzyme activity modifier equations through the development of global data fitting templates in Excel
The classical way of defining enzyme inhibition has obscured the distinction between inhibitory effect and the inhibitor binding constant. This article examines the relationship between the simple binding curve used to define biomolecular interactions and the standard inhibitory term (1 + ([I]∕Ki))....
Main Author: | Ryan Walsh |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-12-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/6082.pdf |
Similar Items
-
Enzyme inhibition by tropical drugs
by: Purba, H. S.
Published: (1984) -
Recent Advances in Electrochemical Biosensors Based on Enzyme Inhibition for Clinical and Pharmaceutical Applications
by: Loubna El Harrad, et al.
Published: (2018-01-01) -
Binding determinants for some glutathione-dependent enzymes
by: Al-Timari, A. A. A.-K.
Published: (1985) -
Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking
by: José L. Medina-Franco, et al.
Published: (2014-02-01) -
Advances in Enzyme-Based Biosensors for Pesticide Detection
by: Bogdan Bucur, et al.
Published: (2018-03-01)