HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors

Since the human immunodeficiency virus (HIV) was discovered as the etiological agent of acquired immunodeficiency syndrome (AIDS), it has encouraged much research into antiviral compounds. The reverse transcriptase (RT) of HIV has been a main target for antiviral drugs. However, all drugs developed...

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Bibliographic Details
Main Authors: Greg L. Beilhartz, Matthias Götte
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Viruses
Subjects:
HIV
Online Access:http://www.mdpi.com/1999-4915/2/4/900/