Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Abstract Background Delayed reconstruction of transection or laceration injuries of peripheral nerves is inflicted by a reduced regeneration capacity. Diabetic conditions, more frequently encountered in clinical practice, are known to further impair regeneration in peripheral nerves. Chitosan nerve...

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Bibliographic Details
Main Authors: Lena Stenberg, Maria Stößel, Giulia Ronchi, Stefano Geuna, Yaobin Yin, Susanne Mommert, Lisa Mårtensson, Jennifer Metzen, Claudia Grothe, Lars B. Dahlin, Kirsten Haastert-Talini
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Neuroscience
Subjects:
Chitosan nerve guide
Delayed nerve reconstruction
Diabetes
Regenerative matrix
Immunomodulation
Online Access:http://link.springer.com/article/10.1186/s12868-017-0374-z

Internet

http://link.springer.com/article/10.1186/s12868-017-0374-z

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