Myo-Inositol Transporter SLC5A3 Associates with Degenerative Changes and Inflammation in Sporadic Inclusion Body Myositis

Myo-Inositol Transporter SLC5A3 Associates with Degenerative Changes and Inflammation in Sporadic Inclusion Body Myositis

Myo-inositol exerts many cellular functions, which include osmo-protection, membrane functioning, and secondary messaging. Its Na<sup>+</sup>/myo-inositol co-transporter SLC5A3 is expressed in muscle tissue and further accumulates in myositis. In this study we focused on the peculiar sub...

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Bibliographic Details
Main Authors: Boel De Paepe, Caroline Merckx, Jana Jarošová, Miryam Cannizzaro, Jan L. De Bleecker
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
sporadic inclusion body myositis
myo-inositol
protein aggregation
inflammation
Online Access:https://www.mdpi.com/2218-273X/10/4/521

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